PKBio offers a wide range of in vitro toxicity and drug testing of LDC (lead drug candidates),  NCEs (new chemical entities) and NBEs (new biological  entities)  in a number of neuronal and non-neuronal  cell lines. 

PK Biosciences provides fast turnaround for in vitro drug-discovery toxicity studies

In vitro screening

The technology  offer is a cell based in-vitro toxicological screening system that can be used in the toxicology testing of a drug candidate or other chemical compound that needs to be tested. This screening system is relevant for all industries producing chemical or biological compounds that will ultimately come in contact with humans. 

Human immortalized and primary cell lines that have been selected over a long time to be highly specific for toxicology tests.

Choice of neuronal and non-neuronal cell lines models derived from different tissues, species and representative of various cancer, neurodegenarative and other diseases.

Choice of neuronal and non-neuronal cell lines

SHSY5Y, PC12, HL60, HepG2, NIH3T3, DU145, PC3, HT29, HCT116, Molt-4, HEK293, TE671 and more.

Choice of Primary cell lines

Choice of primary neuronal and non-neuronal cell lines models derived from different tissues, species and representative of various cancer, neurodegenarative and other diseases.

Choice of HT-Toxicity Assays

• Oxidative stress assays
• Cytotoxicity assays
• Mitochondrial Assays
• Apoptosis assays
• Autophagic assays
• Proteasomal Assays
• Protein Kinase assays
• Caspase assays